I have designed 3 SharePoint courses for end users.
Lists - Why? Because as an end user, this is where you will find the most value. It’s relatively easy to learn, and once you get it, you will find endless uses for it. Most of your spreadsheets will become redundant, and if you need to fill in a form and send it to someone, you can use this too. You don’t have SharePoint Enterprise Features (Excel Services or InfoPath). You just need access to core SharePoint and Excel 2007.
Permissions - Why? Because as a site owner or site collection administrator, you have to understand how this works or you will end up redesigning your site. This is where the biggest confusion comes in for most site owners and administrators. In fact most guru's can't even agree how it should be done. I have come up with a unique way to make the penny drop so you can decide for yourself, and it involves you getting tied up! ;-) (Really).
Mentorship Program - Why? Because having a mentor for a couple of months can save you 2 years worth of work. If you have been tasked with becoming the resident SharePoint Champion this is for you, but take note of the pre-requisites. This is a unique program in the industry; there is nothing else like it out there. This is my specialty as this is where my biggest issue was when I was still learning, so I decided to provide this service.